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The Top 5 Milk Thistle Supplements Of 2021

Updated 12/02/2021

Learn what to look for when choosing the right milk thistle supplement for optimal liver health.

When it comes to your health, your liver is the unsung hero. It's responsible for helping with the metabolic process, digestion, and proper blood circulation, as well as naturally detoxifying your body.

Unfortunately, most of us abuse our liver and often, without even knowing it, by: 

Indulging in a high-fat and high-sugar diet

Drinking too much alcohol

Regular use of over-the-counter pills

Carrying just a little extra weight in your midsection 

When there’s too much of these toxins and fatty cells, your liver is not able to work fast enough to break it down and get rid of it. So instead, it holds on to this extra waste, which then creates a blockage in your liver.

This makes it hard for your liver to function properly and can cause some serious and potentially fatal health issues, such as liver scarring.

How Milk Thistle Helps Repair Your Liver

New research shows that milk thistle can help reverse damage caused by toxins and improve liver function. Taking it regularly can help your metabolic process run smoothly and help you maintain a healthy weight.

Damaged and fatty liver is becoming an epidemic, so it’s no wonder that the market today is flooded with hundreds of milk thistle supplements that promise to reverse the damage and help heal your liver.

However, not all milk thistle products are created equally. Many brands will cut corners, filling their supplements with harmful additives and using ineffective ingredients or weak dosages.

That’s why Consumer Survey created this guide to help you better understand what to look for in a great milk thistle supplement that will deliver noticeable results. We’ve also researched 74 of the top milk thistle supplements to uncover the good, the bad, and the downright ugly.

How Can A Quality Milk Thistle Supplement Improve Your Health? 

But before we dive into how to find the right milk thistle supplement, it’s important to understand how a top-notch milk thistle supplement can help improve your overall health.

Studies Show A Quality Milk Thistle Supplement Can:

Cleanse your liver of toxins

Breakdown excess fat in the liver

Improve blood circulation

Increase your energy levels

Protect your liver from future damage

Help with weight management

But to get these amazing health benefits, it’s important to find a milk thistle supplement that also contains the following ingredients.

Other Liver Health Ingredients To Look For: 


Tocotrienols are a very powerful member of the vitamin E family. Studies have found evidence that this potent ingredient can help cleanse your liver of toxic fat cell buildup. We recommend 3 - 5 mg.


Various studies have shown that zinc can help protect your liver from damage by reducing the fatty buildup in your liver. We recommend no more than 15 mg.


Selenium is able to help cleanse your liver from harmful buildup by encouraging the production of an antioxidant that can help heal damaged liver tissue cells and promote elasticity.

Alpha Lipoic Acid

This vital antioxidant is naturally occurring in the body and plays a strong role in metabolism. Alpha Lipoic Acid is widely thought to help support optimal liver function and aid in the liver's breakdown of fat cells. We recommend approximately 100 mg.

BEWARE: Magnesium Stearate & Titanium Dioxide

These cheap fillers are used to help bind ingredients together and lubricate the supplement so it doesn’t gum up when it is run through the manufacturing machines. Magnesium stearate adds no nutritional value and can become toxic to your system. While titanium dioxide can compromise the health of your immune system. Low-quality liver health supplements typically include these fillers.

Your Definitive Milk Thistle Supplement Checklist 

Ingredients aren’t the only important thing to watch out for. Here’s what else you need to pay attention to before buying a milk thistle supplement

Money-back Guarantee

Look for a company that feels so confident in their product that they're willing to offer at least a 90-day 100% money-back guarantee. This shows that the company has invested the time and resources to create a product that can deliver results.

Clinically Studied Ingredients

It's the golden rule. Always keep an eye out for clinically studied ingredients that have the science to back up their claims. For example, many liver supplements contain milk thistle, but not all varieties have been clinically tested and proven to achieve effective results. Some generic versions are often watered-down and unable to help your liver.

 Clinically Recommended Dosages 

Just because a brand uses quality ingredients, doesn’t mean you’re getting the right dosage to experience optimal results. Some brands will use quality ingredients, but skimp out on dosages in order to save money. We recommend looking for a supplement that lists at least 80 mg per serving of clinically studied milk thistle.

Relying On Amazon Reviews

  1.  Amazon is a fantastic marketplace and resource for many consumers, but sadly relying only on Amazon reviews can be tricky. That's because up to 60% of reviews on Amazon were paid for by shady third party companies. So when it comes to shopping on Amazon, just make sure to be extra vigilant and take it with a grain of salt. 

The Results Are In...

After surveying over 8,000 user reviews and then carefully reviewing 74 products, only a select few passed our strict testing criteria listed above. Users reported enhanced health — from quicker metabolism and increased energy — sharper mental clarity, and more. Here are our top 5 picks for the best milk thistle supplements on the market today.

Top Picks are updated monthly based on testing and analyses:

Top Pick

5 stars

Consumers Survey Recommended

  • Formulated with quality, clinically studied ingredients
  • Uses clinically recommended dosages
  • Free from additives or fillers
  • 90-day money-
    back guarantee

#1: LiverMD By 1MD Nutrition™


LiverMD™ is formulated with powerful, clinically studied ingredients: EvnolMax®, which is a clinical strength tocotrienol, and Siliphos®, the bioavailable active ingredient in milk thistle. LiverMD™ is also made with zinc, selenium, and other ingredients that work to help detox and repair your liver.

This was one of the only products that we could verify had no hidden additives or fillers. It was also one of the only liver health supplements that was third-party tested.

Additionally, 1MD Nutrition™ offers a 90-day, risk-free, money-back guarantee, proving the company stands behind its products.

All in all, 1MD Nutrition™ is our top pick.


Buy Now > >


4 stars

Call Live Conscious:

#2: LiverWell By Live Conscious

LiverWell by Live Conscious is a great liver health supplement and falls just shy of being the best.

Live Conscious formulated their product with stand out ingredients, such as Siliphos® Bioavailable silybin milk thistle extract, which has been clinically shown to aid in both liver and kidney function.

And with a 365-day money-back guarantee, Live Conscious stands by their products making them the clear choice for #2 on our list.

 Buy now > >


5 stars

Call Gaia Herbs:


#3: Milk Thistle Seed By Gaia Herbs

Gaia Herbs' Milk Thistle Seed is a pure formula that really highlights milk thistle.

This formulation is free from harmful additives and fillers. However, it does not contain any supportive ingredients like zinc or selenium that might make this formulation stronger.

This product appears to have high reviews on Amazon and is big on transparency. This said, Gaia Herbs only offers a 45-day money-back guarantee, which doesn't give customers much time to try this product.

 Buy Now > >


5 stars

Call :
(855) 803-1275


#4: Liver Cleanse by ProBiome RX

This all-natural supplement is entirely herbal and probiotics-based. While it does contain milk thistle, it lacks several key ingredients.

Liver Cleanse does not contain zinc, selenium, or any form of Vitamin E. This limits ability to support your liver health. 

Also, it uses generic herbs. We cannot guarantee the quality of any of its ingredients, including that of its milk thistle.

However, we commend ProBiome RX's commitment to all-natural ingredients. That's why we give Liver Cleanse the #4 spot on this list.

 Buy Now > >


5 stars

Call :
(888) 328-9992


#5: Liver Support by Vital Nutrients

Liver Support by Vital Nutrients finishes off our list. While this supplement does contain a 200 mg of milk thistle, it contains very few other liver-supporting ingredients.

It lacks zinc, selenium, or any form of Vitamin E. Worse, this supplement contains fillers like magnesium silicate, which might be harmful to your system.

However, its strong dose of milk thistle and uncommon liver support ingredients do distinguish it from other supplements. It earns the #5 spot on our list.

 Buy Now > >

P.S. While 1MD Nutrition™ has the best milk thistle supplement we've found, we would still love to hear about any others you've tried. If you have had a great experience of your own, please send me an email to Beverly@ConsumersSurvey.org with the details.

Beverly Gratson,
Senior Health Editor

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  • 1. Research First we conduct in-house research with a highly qualified editorial team comprised of individuals who specialize in various fields.

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