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2024's Top NAC Supplements for Building a Stronger Immune System

Updated 11/13/2024

Learn which NAC supplements best support immune health & remove bodily toxins

For years, doctors have used N-Acetyl Cysteine, or NAC for short, to treat conditions ranging from heart and lung to mental health.

More recently, however, researchers have lasered in on NAC's amazing immune-boosting capabilities. 

Now NAC is more popular than ever among people seeking a natural approach to immune health. However, companies have flooded the market with NAC, forcing consumers to sift through poor and mediocre products. 

We're here to cut through the noise and confusion. After analyzing dozens of brands, we've compiled a list of our top 5 favorite NAC-containing supplements the market has to offer. 
 

Benefits of Taking NAC:

  • Replenishes natural antioxidant levels
  • Protects against free radicals
  • Helps repair damage to the liver
  • Fortifies the immune system
  • Helps reduce inflammation from oxidative stress
  • Aids in cellular detoxification

 
What Is NAC And How Does It Work?

NAC is the supplemental form of L-cysteine, a semi-essential amino acid present in our bodies. Over the decades it's been used to treat a host of medical issues, including chronic lung disease and addictive behavior.

In fact, the effectiveness of NAC is so well-documented, the World Health Organization has designated it an "essential medicine." NAC is making headlines once again, this time thanks to its immune-boosting properties.

Specifically, NAC is valued for its role in producing a powerful antioxidant called glutathione (GHS). Often dubbed the "master detoxifier," GHS eliminates free radicals and heavy metals from the body and protects against the harmful effects of inflammation.

Over time, your body produces less of this vital antioxidant. However, studies have shown that taking NAC can boost GHS production.  
 

Your NAC Immune Supplement Should Contain:
 

600 mg of NAC

Look for a supplement that contains at least 600 mg of NAC per serving. Clinical studies suggest this to be the smallest effective dose.

Milk Thistle

Recent research has shown that milk thistle can help reduce and reverse damage caused by free radicals and toxins. It can also improve liver function, thus helping your metabolic processes run more efficiently.

Zinc

Various studies have shown that zinc is essential to immune function and plays an important role in reducing inflammation.

Selenium

This powerful natural ingredient is vital for helping to heal and detoxify your liver. It also plays a key role in reducing inflammation from oxidative stress and enhancing immunity.

What to avoid

Magnesium Stearate

This cheap filler is used to help bind ingredients together and lubricate the supplement so it doesn’t gum up when it is run through the manufacturing machines. Magnesium stearate adds no nutritional value and can become toxic to your system.

Titanium Dioxide

Widely relied upon in supplement manufacturing as a coloring agent and binding mineral, titanium dioxide can compromise the health of your immune system. Low-quality supplements often use this filler.

The Results Are In...

We've made our list and checked it twice. Here are our top 5 picks for immune supplements with NAC. 

Top Picks are updated monthly based on testing and analyses:


Top Pick

5 stars

Consumer Survey Recommended

  • 800 mg of NAC
  • Siliphos® Clinically Studied Milk Thistle
  • 200 mcg of Selenium
  • 15 mg of Zinc
  • 100 mg of Alpha Lipoic Acid
  • Zero artificial additives or fillers
  • 365-day money-
    back guarantee

1. LiverWell by LiveConscious

rating

LiverWell contains 800 mg of high-quality NAC, making it an excellent product for immune and respiratory health.

It also includes clinically studied milk thistle extract, Siliphos®, 15 mg of zinc, and  200 mcg of selenium, which all act synergistically with NAC to fortify the liver and promote overall immune health.

All of LiverWell's ingredients are third-party tested for quality and effectiveness. It contains no artificial additives or fillers.

Additionally, LiveConscious offers a 365-day return policy, so you can try their products completely risk-free.
 

 Buy now > >

Rating

5 stars


 

2. LiverWise by HealthWise

Great NAC Supplement

LiverWise contains 800 mg of high-quality NAC. It also includes selenium, milk thistle, and zinc, which work together with NAC to support the immune system and promote respiratory health.

Unfortunately, LiverWise only contains generic ingredients without studies showing their effectiveness. It also contains soy.

This said, LiverWise still contains a great list of ingredients, making it our #2. Additionally, HealthWise offers a 90-day return policy, so you can try their products risk-free.
 

 Buy now > >

Rating

5 stars

 

 

3. Anti-Alcohol by Life Extension

Good NAC Supplement

NAC by Eagleshine Vitamins contains 1200 mg of NAC per serving. It also contains 8 mg of zinc and 25 mcg of selenium.

It has milk thistle extract to boost antioxidant activity, though it is generic and not clinically studied.

Eagleshine Vitamins offers a 60-day money-back guarantee, which is good but falls below our recommended 90-day guarantee. Customer reviews for this product are generally positive. 

Buy Now > >

Rating

3 stars

 

4. NAC By Fresh Nutrition

Adequate NAC Supplement

Fresh Nutrition's NAC contains a strong 880 mg dose of NAC per serving. It contains no other ingredients.

While this dosage meets expectations, its lack of key ingredients greatly limits its immune support. Its 30-day money-back guarantee also falls behind other top supplements.

However, its dosage does stand out from other strictly-NAC supplements, and it contains no artificial fillers. That earns it a spot on our Top 5.

Buy Now > >

Rating

2.5 stars

 

 

5. NAC By Integrative Therapeutics®

Average NAC Supplement

NAC by Integrative Therapeutics contains just 600 mg of NAC per serving.

Integrative Therapeutics' dosage just barely meets our criteria. Considering its lack of any other key ingredients, this supplement leaves much to be desired. Also, it does not have a clear return policy.

However, it leaves out artificial fillers and is clinician-developed, giving it a place on our Top 5.

Buy Now > >


P.S. While Live Conscious offers the best NAC-containing immune supplement we've found, we would still love to hear about any others you've tried. If you have had a great experience of your own, please send me an email to Beverly@ConsumersSurvey.org with the details.

Sincerely,
Beverly Gratson,
Senior Health Editor

Back to Our #1 Choice

 

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